Twenty-two percent of children with juvenile localized scleroderma have extracutaneous manifestations, and nearly half of those cases have joint involvement. (Zulian F et al. 2005; 52:2873-2881.) ...

Scleroderma is a rare, autoimmune condition in which the body produces too much collagen, causing the skin and connective tissue to thicken. Medical News Today Health Conditions ...

There are two types of scleroderma. Localized scleroderma is confined to the skin on the hand and face while in systemic scleroderma the disease could spread to the internal organs.

If other organs are affected you have systemic scleroderma. With localized disease, your scleroderma symptoms may include: Swelling, stiffness, or pain in the fingers, toes, hands, feet, or face; ...

A parent is concerned because her 9-year-old daughter has been diagnosed with "localized scleroderma," after years of seeing physicians and not getting a diagnosis. A dermatologist told her to do ...

A: Scleroderma (systemic sclerosis) is a potentially serious disease, but based on your daughter's age and the fact that it has been so localized for three years, I suspect she does not have one ...

There are more than 50 companies that are developing therapies for the treatment of Scleroderma. Lenabasum (Corbus Pharmaceuticals) and Iloprost (Eicos Sciences) are in the most advanced stage ...

There are two major forms of Scleroderma: localized scleroderma and systemic scleroderma. In localized scleroderma the changes are usually found in only a few places on the skin and muscles.

The Michigan chapter of the Scleroderma Foundation hosted its 40th annual Stampede Scleroderma event at the Detroit Zoo in Royal Oak. Attendees could choose to enter the 5K run, 1-mile run or 1 ...

Weibel L et al. (2007) Laser Doppler flowmetry for assessing localized scleroderma in children. Arthritis Rheum 56: 3489–3495 ...

Clinical enrollment for an open-label, single-arm Phase 1/2 trial of FCX-013 was initiated in August 2018. Fibrocell Science announced that the Food and Drug Administration (FDA) has granted Fast ...

Long-term methotrexate therapy was a beneficial, well-tolerated treatment for juvenile localized scleroderma, according to study results. Researchers in Italy evaluated 65 patients with juvenile ...