A ligand is an ion or small molecule that binds to a metal atom (in chemistry) or to a biomolecule (in biochemistry) to form a complex, such as the iron-cyanide coordination complex Prussian blue ...

Research co-led by University of Toronto researchers and Insilico Medicine has demonstrated the potential of quantum ...

University of Missouri researchers and collaborators have developed a new chemical tool that could help lower the cost of ...

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and ...

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

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The method presents a strong foundation for broader applications in identifying physiologically and pharmacologically relevant membrane protein-ligand interactions. Integral membrane proteins (IMPs) ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

The Department of Chemistry and Biochemistry is currently accepting applications for Fall 2025. Completed applications will be reviewed in the order that they are received. Online applications are ...

Substrate and inhibitor binding are distinguished by major TM rearrangements and their ligand binding chemistry, with TM4 playing a central role in all conformational transitions. Furthermore, our ...

Biophysics Graduate Program, The Ohio State University, Columbus, Ohio 43210, United States Department of Chemistry & Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States ...