Ligand is a biopharmaceutical company enabling scientific advancement through supporting the clinical development of high-value medicines. Ligand does this by providing financing, licensing our ...

The therapeutic landscape of small cell lung cancer (SCLC) is undergoing a paradigm shift with the emergence of delta-like ligand-3 (DLL3)–directed therapies, particularly tarlatamab, a first-in-class ...

First Quarter 2025 Financial Results Total revenues and other income for the first quarter of 2025 were $45.3 million, compared with $31.0 million for the same period in 2024, with the 46% increase ...

By Colin Kellaher Ligand Pharmaceuticals has struck a deal to combine its Pelthos Therapeutics unit with Channel Therapeutics in a bid to accelerate the commercialization of its Zelsuvmi treatment ...

Ligand and Channel Therapeutics to merge in $50 million deal to launch Zelsuvmi for molluscum and advance NaV 1.7 chronic pain programs.

This phase I-Ib trial evaluated a novel CD40L blocking antibody, BMS-986004, for the prevention of graft-versus-host disease (GVHD) after unrelated donor allogeneic hematopoietic cell transplantation ...

These modules allow the ProteinReDiff framework to capture intricate protein–ligand interactions, improve the fidelity of binding affinity predictions and enable more precise redesigns of ...

Simplified redesign of proteins to improve ligand binding Date: January 21, 2025 Source: University of Alabama at Birmingham Summary: The ability to alter proteins to refine control over binding ...

Drug efficacy often correlates better with dissociation kinetics than binding affinity alone. To study binding kinetics computationally, it is necessary to identify all of the possible ligand ...

JUPITER, Fla.-- (BUSINESS WIRE)--Ligand Pharmaceuticals Incorporated (Nasdaq: LGND) today reported financial results for the three and nine months ended September 30, 2024, and provided an ...

Revolutionary visible-light-antenna ligand enhances samarium-catalyzed reactions The ligand makes it possible to use more stable trivalent samarium compounds, which get reduced to divalent ...

Hundreds of protein-ligand interactions have been identified through a collaboration between the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Pfizer. Georg ...