Researchers demonstrated a Ni-catalyzed 1,2-hydroxylarylation of homoallyl alcohols enabled by a bulky β-diketone ligand. They found that the bulky β-diketone ligand (Amacac) plays a crucial ...

Pharmaceutical Biochemistry examines the biochemical and molecular mechanisms of drug interaction. Topics include basic aspects of molecular complementarity (molecular recognition), specificity and ...

dynamics and ligand binding via unnatural amino acid incorporation. At Wilkes University, Henkels will be teaching general chemistry and biochemistry lecture and laboratory courses, as well as ...

The key to this is the modification of the original ligand with a reactive "handle" that allows it to react with a nucleobase at the RNA binding site. This was first demonstrated in vitro and in ...