A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science.

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, ...

Studies have shown that the antidepressant effects of esketamine are rapid and significant, whether a single low dose of esketamine is effective in IBS deserves further investigation. In this study, ...

Our findings show that ketamine and esketamine may be more efficacious than placebo at 24 hours. How these findings translate into clinical practice, however, is not entirely clear. The evidence for ...

Does the intensity of dissociation predict antidepressant effects 24 hours after infusion of racemic ketamine or esketamine in treatment-resistant depression? A secondary analysis from a randomized ...

The postpandemic surge in demand for antimicrobial drugs has accelerated the customization of suitable catalysts, fostering a synergy between their structure and activity in promoting the ...

The [3 + 2] cycloaddition of Lewis acidic alkenylboranes with aldehydes is described, providing a high-yielding and stereoselective approach for the synthesis of five-membered boron-containing ...