UC Davis researchers developed JRT, a modified version of LSD that promotes neuroplasticity without hallucinogenic effects. Tested in mice, JRT enhanced brain connectivity, showed antidepressant ...

JRT has the same molecular weight and general shape as LSD. But that small atomic switch made it behave very differently. It became highly selective for the 5-HT2A receptor—the key site for ...

Lysergic acid diethylamide, or LSD, is best known for its powerful mind-altering effects. But in recent years, researchers have discovered that LSD and similar compounds can also promote ...

“The for-profit model can be abused,” she said. ... The new company’s target was not LSD but a far more obscure substance: 5-MeO-DMT, also known as “the God molecule.” ...

Scientists Tweaked LSD’s Molecular Structure and Created a Wild New Brain Drug This new compound could be a game changer. May 17, 7:30 AM EDT / Victor Tangermann ...

The new molecule could lead to treatments for mental illnesses like depression and schizophrenia, neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease, traumatic brain ...

Psychedelic drugs, such as lysergic acid diethylamide (LSD), can increase neuronal growth, which can have therapeutic effects for conditions such as schizophrenia. However, such drugs can induce ...

UC Davis Health developed a custom AI model called BE-FAIR to identify patients most at risk of hospitalization and reduce care disparities. Sacramento Business Journal. Select a City ...

NPR science podcast Short Wave brings us the stories of how Fiddler crabs drum their mating songs into the sand, growing chicken nuggets in the lab, and a drug like LSD -- without the trip.

UC Davis researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that harnesses the psychedelic’s therapeutic power with reduced hallucinogenic potential.

Reference: Tuck JR, Dunlap LE, Khatib YA, et al. Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential. Proc Nat Acad Sci USA . 2025. doi: 10.1073/pnas.2416106122 This ...