Orange County officials celebrated this week the grand opening of the OC Health Care Agency’s new Irvine campus, designed to ...

Doctors at City of Hope Orange County say there's a great need for increased cancer research and access to treatment in O.C., ...

A dangerous police chase through several cities in Orange County ended with a crash and a deadly police shooting.

Officers with the Anaheim Police Department are in pursuit of a suspect for an unknown want Wednesday evening. The suspect is behind the wheel of a white pickup truck. Sky5 is overhead.

Police opened fire on a driver who was believed to be armed following a chase that ended in Santa Ana on Wednesday. Law ...

City of Hope is on its way to opening Orange County’s first hospital dedicated exclusively to cancer care around the end of ...