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This important work offers a fresh perspective central to merozoite surface biology and potential implications on vaccine design, challenging the dogma that MSPs are indispensable invasion engines.
Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
15don MSN
Malaria is a life-threatening disease affecting people globally. It is spread by mosquitoes carrying Plasmodium parasites ...
Most responses induced in response to many polymorphic targets may not be protective and act as a 'smoke-screen', and hypergammaglobulinemia, a common feature of P. falciparum infection, may ...
15d
News Medical on MSNNew clues to how immune cells fight – and are fooled by – malariaResearchers from The University of Osaka found that both inhibitory and activating killer immunoglobulin-like receptors on natural killer (NK) cells ...
Plasmodium falciparum uses RIFIN proteins to bind to the inhibitory receptor KIR2DL1 on natural killer (NK) cells, thereby evading their attack. Conversely, NK cells can recognize RIFIN via the ...
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