Furthermore, glycine ameliorates hepatic inflammation by inhibiting the nuclear factor-kappa B signalling pathway through glycine receptors. Combination therapy with IFN-α effectively suppressed HBV ...

Moreover, it will explore the difference between inflammation-suppressing and pro-resolution approaches and how this links to inflammasomes. Finally, we will investigate new avenues for targeting ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that ...

Our pathway analysis of meningeal inflammation and areas of inflamed adjacent brain parenchyma suggested that inflammatory signals increased in meningeal inflammation could have variable ‘penetration’ ...

By seeing pathway similarities for divergent diseases—and pathway differences for closely related diseases—developers can head off inflammation more effectively.

Synergistic Inhibition of Pro-Inflammatory Pathways by Ginger and Turmeric Extracts in RAW 264.7 Cells Xian Zhou 1* Gerald Münch 2 Hans Wohlmuth 1,3,4 Sualiha Afzal 2 Ming-Hui (Tim) Kao 2 Ahmad ...

We also carefully analyzed the nicotine dosage to determine its safe and effective range. Furthermore, we summarized the molecular mechanism of nicotine in these inflammatory diseases through ...

Not all inflammation is created equal. While acute inflammation has evolved as the immune system's first response to protect the body, chronic inflammation can cause extensive and potentially ...

Schematic diagram illustrating mechanistic pathways involved in the pathogenesis of myocyte damage and replacement-type myocardial fibrosis in different genetic forms of arrhythmogenic cardiomyopathy.

The inflammatory bowel diseases (IBDs) are chronic intestinal disorders that are typically categorized as one of two subtypes: Crohn’s disease and ulcerative colitis. 1 Ulcerative colitis is ...