The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

Statins may limit inflammation involved in the development of these complications. Objectives We tested the hypothesis that perioperative simvastatin use reduces postoperative cardiopulmonary ...

Colorectal Cancer (CRC) Incidence: Confirmed CRC cases (699 total: 462 colon, 237 rectal) over 585,644 person-years (median ...

Newly discovered mechanisms associated with chronic muscle inflammation in Duchenne muscular dystrophy (DMD) could point the way to new therapeutic options to slow progressive muscle weakness in ...

Obesity can lead to a chronic inflammatory state within the body. What drives this inflammation? Does inflammation, in turn, promote obesity? And what are the potential therapeutic implications?

ABSTRACT: Background: Chronic inflammation appears to be a pivotal mechanism underlying the pathophysiology of metabolic syndrome (MetS). Increasing evidence highlights the role of cytokines and their ...

This review provides an in-depth exploration of the potential of Ginsenoside Rg1 in the treatment of Parkinson’s disease (PD). The emphasis of this article was the therapeutic mechanisms of Rg1, which ...

In animal models, NU-9 was found to show promise in treating Alzheimer's by reducing toxic protein buildup and brain inflammation.

Prolonged exposure to these conditions could explain why standing may increase the risk of cardiometabolic disease. Enhanced oxidative stress (toxin—inflammation mechanism): Prolonged standing may ...

The research team led by Professor Chen Haiyong (middle) discovers a mechanism of C-reactive protein that exacerbates inflammation in diabetic kidney disease.