Regulation of the immune response is crucial for avoiding an excessive inflammatory response. Here, recent advances in our understanding of the regulation of mitogen-activated protein kinase (MAPK ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

Hepatitis B virus (HBV) infection is known to be associated with the risk of hepatocellular carcinoma (HCC), but how and why ...

An international research team has published a study in the journal The FEBS Journal that significantly advances the ...

We are continuing to explore how the lysosome regulates macrophage function and inflammation in LSDs and other conditions ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

A recent study published in Genes & Diseases explores the clinical implications of loss-of-function mutations in IKBKG/NEMO, ...

Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in men worldwide. However, the mechanisms controlling the early stages of prostate cancer ...

This valuable manuscript provides convincing evidence that BK and CaV1.3 channels can co-localize as ensembles early in the biosynthetic pathway, including in the ER and Golgi. The findings, supported ...

Additionally, it is associated with hypertension, coronary artery disease, and strokes due to its impact on lipid metabolism and inflammation.

There is, however, a need for improved understanding of the caries process, as well as the mechanisms of pulpal inflammation and repair, to better inform clinical practitioners.<br/> <br/>This ...