More information: Teresa Porqueddu et al, Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration, Communications Biology (2025 ...

In vitro enteroid-derived three-dimensional tissue model of human small intestinal epithelium with innate immune responses. PLOS ONE , 2017; 12 (11): e0187880 DOI: 10.1371/journal.pone.0187880 ...

In the new study, the team used the model to demonstrate that as Alzheimer’s pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and ...

It's starting out by modeling the human immune system in a dish. ... Unlike brain or kidney organoids, which are tiny 3D models of those organs, immune cells such as B cells, ...

Researchers have developed miniature 3D human colons enriched with immune cells, ... an immune system. ... complete human organs and are not connected to a larger bodily system like animal models.

CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic ...

Scientists have a new tool to help them tease out the immune system's mysteries. Researchers cultured human B and T cells inside a microfluidic Organ Chip and coaxed them to form functional ...

Moreover, using deep learning, AlphaFold was able to predict the 3D structures of 200 million known proteins. ... AI models of the human immune system could revolutionize biomedical discovery, ...

Scientists have employed mouse models in immunological studies for over a century; however, these models, much like other systems, are unable to perfectly recapitulate the human immune system. To ...

To better understand why some cancer patients struggle to fight off infections, Georgia Tech researchers have created tiny lab-grown models of human immune systems. These miniature models — known as ...

A type of mouse widely used to assess how the human immune system responds to transplanted stem cells does not reflect what is likely to occur in patients, according to a study by researchers at the ...