In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...

Results: A decrease in intestinal iron absorption occurred following an oral dose of iron and this was associated with increased enterocyte iron levels, as assessed by iron regulatory protein activity ...

Apoptotic/cell death markers were evaluated by flow cytometry. qPCR and immunoblotting were applied to quantify gene and protein expression. Results miR-181a-5p expression was increased in human FJ OA ...

Samples were resolved on precast 4–20% SDS/PAGE Gels (Expedeon, CA, USA) and transferred to nitrocellulose membranes prior to immunoblotting with antibodies against endothelial nitric oxide synthase ...

The antibodies used for immunoblotting include: rabbit anti-SARS-CoV-2 S2 (Sino Biological, 40590-T62, 1:2000), mouse anti-SARS-CoV-2 N (Sino Biological, 40143-MM05, 1:1000), rabbit anti-ACE2 ...

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Aspiring participants of the GATE 2025 Biotechnology (BT) exam must go through the syllabus of Biotechnology (BT). The detailed syllabus for GATE 2025 Biotechnology is made available by IIT Roorkee ...

Collective migration plays critical roles in developmental, physiological and pathological processes, and requires a dynamic actomyosin network for cell shape change, cell adhesion and cell-cell ...