Methods: We searched PubMed for studies published before January 2010 on the diagnosis of TB in children using an IGRA. We compared the specificity and sensitivity of the tuberculin skin test (TST ...

In high-income western countries, interferon-γ release assays (IGRAs) have largely replaced the classic tuberculin skin test for diagnosing latent tuberculosis (TB). They appear promising for ...

IAVI and Biofabri are collaborating on the trial, which will recruit around 4,300 patients with latent TB infections across four countries.

A 15-year study by Kaiser Permanente Northern California reveals significant gaps in LTBI testing practices, highlighting the need for targeted strategies to prevent active TB cases.

They looked towards the interferon-gamma release assay (IGRA), a blood test initially developed to diagnose bTB in cattle. It works by measuring the levels of interferon-gamma (IFN-γ), a molecule ...