In T cells, MTOC polarization also requires CDC42 (cell-division cycle 42) 43 and activation of a signalling platform comprising ZAP70 (ζ-chain-associated protein kinase of 70 kDa), SLP76 (SRC ...

Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to properly ... This work is supported by the National Institutes of Health ...