This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

Epigenetic clocks that quantify rates of aging from DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer’s disease (AD), ...

Dendritic cells (DCs) are critical in the maintenance of self-tolerance and altered functions of DCs have been implicated in the pathogenesis of a number of autoimmune diseases, such as rheumatoid ...

Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

leading to higher rates of certain autoimmune disorders(1 Trusted Source The risk of immune-mediated inflammatory diseases following exposure to childhood maltreatment: A retrospective ...

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to ...

Is IBD an autoimmune disease? While it has similarities with autoimmune diseases, IBD is a little different. IBD falls under the umbrella of immune-mediated inflammatory diseases (IMIDs).