The histone lysine methyltransferase DOT1L (DOT1-like histone lysine methyltransferase) is responsible for the epigenetic regulation of gene expression through specific methylation of ... and clinical ...

Studies of immune cells and peripheral ... In this study, we will explore DNA methylation and histone acetylation, in the context of ECM gene expression, in ASM cells. We posit that epigenetic factors ...

Epigenetic dysregulation has been strongly implicated in psychiatric disorders. Epigenetic modifications, such as DNA methylation and histone modifications ... The Lasting Consequences of Prenatal ...

Epigenetic modifications, such as changes in DNA methylation, histone modifications ... thereby influencing chronic inflammatory conditions like atherosclerosis and autoimmune diseases, with potential ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in ...

This article was reviewed by Knox Beasley, MD. You might associate autoimmune conditions with symptoms like skin disease, chronic pain, and fatigue. A less-discussed symptom of autoimmune diseases?

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

leading to higher rates of certain autoimmune disorders(1 Trusted Source The risk of immune-mediated inflammatory diseases following exposure to childhood maltreatment: A retrospective ...

Bacteria in the gut have been implicated in autoimmune diseases, like lupus, that don’t primarily affect the gastrointestinal system. But how those bacteria affect the human immune system remains ...

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to ...

Is IBD an autoimmune disease? While it has similarities with autoimmune diseases, IBD is a little different. IBD falls under the umbrella of immune-mediated inflammatory diseases (IMIDs).