Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone | Ebooks ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Historically, therapies for ASD and ID have primarily targeted managing symptoms, such as behavioral issues or communication ...

AUTX-703, a novel and potent oral KAT2A and KAT2B protein degrader, inhibits growth and induces profound, persistent cell state differentiation in SCLC models ...

InsP 6 has the ability to induce apoptosis in HONE-1 nasopharyngeal cancer cells. Apoptosis-inducing ability of InsP 6 can be enhanced by histone application. Combination of InsP 6 and histone ...

Using animal models, he, Dempsey, and the rest of their research team found that H3K36 methylation — a biochemical process that occurs within the H3 histone protein — is responsible for turning that ...