Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Aiming at the problem of sparse information distribution and lack of good correlation between data in the era of big data, this paper proposes a knowledge graph query and reasoning method based on ...

Transforming manufacturing, digital twins integrate AI and real-time data, optimizing processes and enabling proactive ...

Drug screening is the process by which potential drugs are identified and optimized before selection of a candidate drug to progress to clinical trials. It can involve screening large libraries of ...