Whole-mount 3D imaging at the cellular scale is a powerful tool for exploring complex processes during morphogenesis. In organoids, it allows examining tissue architecture, cell types, and morphology ...

This important study presents a new method for longitudinally tracking cells in two-photon imaging data that addresses the specific challenges of imaging neurons in the developing cortex. It provides ...

Katoh, K. and Standley, D.M. (2013) MAFFT Multiple Sequence Alignment Software Version 7 Improvements in Performance and Usability. Molecular Biology and Evolution, 30, 772-780.

Abstract: This paper introduces a simple and effective approach to improve the accuracy of multiple sequence alignment. We use a natural measure to estimate the similarity of the input sequences, and ...

Figure 2. Workflow used for ancestral sequence reconstruction and evaluation. (A) Searching extant sequences from the database and selecting for good variations of ancestral sequences. (B) Curating ...

Keywords: genome analysis, multiple sequence alignment, graph drawing, visualization, genome comparison Citation: Schebera J, Zeckzer D and Wiegreffe D (2024) A layout framework for genome-wide ...

Abstract: Multiple sequence alignment is a fundamental and challenging problem in computational molecular biology. ClustalW, the most widely used multiple sequence alignment software, performs very ...

Abstract Deep learning-based prediction of protein structure usually begins by constructing a multiple sequence alignment (MSA) containing homologs of the target protein. The most successful ...

Multiple sequence alignment is widely used in sequence homology detection, protein secondary and tertiary structure prediction, phylogenetic tree analysis, and other fields. Existing research mainly ...