An uncharacterized chromatin factor ZNF280A is recruited to sites of DNA damage. Credit: Nature Cell Biology (2025). DOI: 10.1038/s41556-025-01674-1 ...

Base editing, which corrects misspellings in DNA, offers an alternative to existing forms of gene therapy, which either add or remove things from the genome. Beam Therapeutics ...

The research is published in the journal Nature. The study comprehensively analyzed "cis-regulatory elements" (CREs), which are the DNA sequences that regulate gene transcription.

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...

As the first crystal structure of this type, the researchers say it will also be useful as a model for other targets in the genome, besides the insulin gene, which form this shape of DNA.

Crucially, the researchers discovered both loops of RNA can be reprogrammed. That means scientists can specify a genomic location as well as what sequence should go there. In theory, the system could ...

Number of gene therapy clinical trials approved worldwide 1989-2017 Ginn SL, Amaya AK, Alexander IE, Edelstein M, Abedi MR. Gene therapy clinical trials worldwide to 2017: An update. J Gene Med ...

graph theory 1 Articles Where Graph Theory Meets The Road: The Algorithms Behind Route Planning April 4, 2024 by Maya Posch 33 Comments ...