Researchers from the National University of Singapore (NUS) have solved a 60-year-old mystery in bacterial cell envelope ...

Background In 2011, there were approximately two million cases of hospital-acquired infections in the United States, more than 75,000 of which were fatal. [1] Gram-negative bacteria cause the four ...

Small, hydrophilic molecules, including most important antibiotics in clinical use, cross the Gram-negative outer membrane through the water-filled channels provided by porins. We have determined the ...