In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine ...

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of ...

Notably, glycolysis, oxidative phosphorylation, histone acetylation, and DNA methylation interact in a tightly regulated network to influence CAR-T cell phenotype and exhaustion, ultimately ...

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and ...

Johns Hopkins researchers identify energy-generating waves on cancer cell membranes, revealing potential targets for slowing ...

CAR-T cells, which are genetically programmed to specifically recognize and kill target cells, have altered the therapeutic landscape of lymphoma. After the tumor antigens are identified by scFv, ...

Previously known examples of resistance genes encoded within fungal BGCs span a wide range of essential biological processes, including the proteasome, glycolysis, oxidative phosphorylation, as well ...

Drug resistance in solid tumors remains a major obstacle in oncology, frequently leading to treatment failure and disease relapse. A central contributor to this resistance is metabolic reprogramming, ...