In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine ...

This led to a decrease in PDHA1 S293 phosphorylation and an increase in PDH enzyme activity, promoting oxidative phosphorylation and reducing glycolysis. The clinical relevance of PDK1 Y163 ...

This led to a decrease in PDHA1 S293 phosphorylation and an increase in PDH enzyme activity, promoting oxidative phosphorylation and reducing glycolysis.

Cells normally make most of their energy via oxidative phosphorylation, but they need oxygen to do so. If oxygen runs short, most cells switch to aerobic glycolysis.

Mitochondrial oxidative phosphorylation is the major pathway for ATP production in eukaryotic cells (Figure 1). During this process, cellular redox energy from the breakdown of food is converted ...

A laboratory study demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been well understood ...

“Accordingly, a substantially different metabolic profile at the level of glycolysis, oxidative phosphorylation, and glutamine metabolism is present in PAH-ECs compared to CTEPH-ECs and suggests ...

Honestly, the whole study was based on the unexpected finding that mitochondrial oxidative phosphorylation is essential early for promoting Th17 cell differentiation and suppressing the emergence of ...