All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as ...

Learn how analytical methodologies can be used to identify RSV pre- and post-fusion proteins for vaccine development.

Objective: This study aims to investigate the relationship between metabolic dysfunction-associated fatty liver disease (MAFLD) and sex hormones and sex hormone-binding globulin (SHBG) in boys with ...

In a new study published in Nature, University of Missouri researchers have, for the first time, revealed the specific shape and structure of one of the body's most important yet complicated proteins: ...

All flow cytometry data were analyzed using the FlowJo software (Tree Star, Ashland, OR). Equal masses of protein lysate or equal volumes of immunoprecipitation eluents were loaded into NuPAGE 4–12% ...

Misregulation of protein–protein interactions (PPIs) underlies many diseases; hence, molecules that stabilize PPIs, known as molecular glues, are promising drug candidates. Identification of novel ...

Mnl1 demannosylates misfolded, globular proteins and Pdi1 then reduces the disulfides to generate unfolded proteins competent for ERAD. This study expands the molecular grammar of FUS, identifying ...

New Cornerstone Science Laboratory, Tsinghua-Peking Joint Center for Life Sciences, Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic ...