CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

Synaptic vesicle exocytosis is the biological process by which a synaptic vesicle fuses with the plasma membrane of the pre-synaptic axon terminal and releases its contents into the synaptic cleft.

A study investigates whether gut-derived GABA can directly increase brain GABA levels, with promising results. While it remains unclear if gut-derived GABA can cross the blood-brain barrier, ...

Chemical synaptic transmission involves the release of a neurotransmitter from the pre-synaptic neuron, and neurotransmitter binding to specific post-synaptic receptors.