When the neurotransmitter binds to the neuron on the other side of the synaptic cleft, ... GABA is the brain’s primary inhibitory neurotransmitter (Buzsaki et al., 2007).

GAT1 functions to transport extracellular GABA, released during transmission, from the synaptic cleft back into the neuron. An existing treatment for epilepsy is the targeted inhibition of GAT1 with ...

Vesicular GABA Uptake Can Be Rate Limiting for Recovery of IPSCs from Synaptic Depression. Cell Reports , 2018; 22 (12): 3134 DOI: 10.1016/j.celrep.2018.02.080 Cite This Page : ...

At inhibitory synapses, these neurons release GABA molecules into the synaptic cleft, the space between neurons where neurotransmitters diffuse. The molecules bind to GABA type A ...