Homeostatic plasticity, the brain's method of preserving equilibrium in neural circuits, relies heavily on spontaneous ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

image: Molecular mechanism diagram of RG7388 inhibiting SFTSV view more Credit: ©Science China Press Researchers from Professor Wang Tao's team at the School of Life Sciences, Tianjin University ...

image: Mechanism diagram: LSD1 deficiency → suppressed FOXO3/mitophagy → mitochondrial dysfunction → ROS → ferroptosis → follicle depletion. view more Credit: ©Science China Press ...

The widespread products using contained antimony and corresponding activities of Sb mining have led to elevated antimony concentrations in water. In order to effectively remove the excessive antimony ...

Chaigui granules were a traditional Chinese medicine (TCM) preparation with antidepressant effects derived from a famous antidepressant prescription. It was of great significance to clarify the ...