While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive ...

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Homeostatic plasticity, the brain's method of preserving equilibrium in neural circuits, relies heavily on spontaneous ...

image: Mechanism diagram: LSD1 deficiency → suppressed FOXO3/mitophagy → mitochondrial dysfunction → ROS → ferroptosis → follicle depletion. view more Credit: ©Science China Press ...

image: Molecular mechanism diagram of RG7388 inhibiting SFTSV view more Credit: ©Science China Press Researchers from Professor Wang Tao's team at the School of Life Sciences, Tianjin University ...

This approach confirms and extends our hypothesis that modulation of GABA A receptors is the underlying mechanism in antipsychotic-like action of olanzapine but not of haloperidol and risperidone.

The widespread products using contained antimony and corresponding activities of Sb mining have led to elevated antimony concentrations in water. In order to effectively remove the excessive antimony ...

Identifying all the possible Li sites in a crystal structure is the first step toward understanding the Li-ion migration in solid electrolytes for Li batteries. Here, we discover that the perovskite ...