Engineering strategies to improve terpenoids’ production in Bacillus subtilis mainly focus on 2C-methyl-d-erythritol-4-phosphate (MEP) pathway overexpression. To systematically engineer the chassis ...

The development of prodrugs — chemically modified versions of pharmacologically active agents that must undergo transformationin vivoto release the active drug — is a well-established strategy ...

Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the ...

With this vision, it is possible to redesign central metabolic pathways such as glycolysis, the pentose phosphate pathway, the TCA cycle and, potentially, a variety of secondary metabolic pathways.

G6PD, expressed in all of the body's tissues, controls the flow of carbon through the pentose phosphate pathway, produces NADPH for reductive biosynthesis, and maintains oxidation-reduction in the ...

The Maui Metropolitan Planning Organization invites the Hāna community and the public to attend the final in-person community meeting for the Hāna Community Pathway Study on Monday, June 23, 6: ...

Introduction Plasmodium vivax is the predominant cause of malaria in the Greater Mekong Subregion. To ensure safe treatment with primaquine, point-of-care glucose-6-phosphate dehydrogenase (G6PD) ...