These knots often form in regions with many guanine (G) bases. They help regulate important processes like transcription, where DNA is copied into RNA. But G4s are double-edged swords.

In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

Fourteen million people worldwide suffer from enlarged hearts, or hypertrophic cardiomyopathy (HCM), a genetic disease that ...

This fragrance opens with the floral brightness of narcissus, layered over a rich quartet of vetiver that brings an earthy, ...

This is the moment a gang of British men recruited as guns for hire by Russia's Wagner mercenary group firebombed a warehouse ...

HARD ON THE GAS Emissions rules will kill the 911 GT3… won’t they? But Porsche’s GT boss has a few tricks up his sleeve Photography Steffen Jahn After 48 hours of dawn-to-dusk Alpine romping in the ...

Electrochemical DNA biosensors detect the redox signal of the target analytes or a hybridization of a specific single-stranded DNA (ssDNA) sequence with its complementary strand, which are accumulated ...

DNA oligomers can form silver-mediated duplexes, stable in gas phase and solution, with potential for novel biomedical and technological applications. The nucleobase-metal bond primarily drives duplex ...

Their findings, published in the Proceedings of the National Academy of Sciences, pave the way for solid-state, label-free DNA sequencing technologies with implications for precision medicine.

DNA nanotechnology is a branch of nanotechnology concerned with the design, study and application of synthetic structures based on DNA. DNA nanotechnology takes advantage of the physical and ...

Study shows aspartame affects gut microbiome and gene expression in glioblastoma, highlighting potential links to cancer ...

Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these types of drugs are 5-azacytidine and 5-aza-2′-deoxycytidine (Egger et al., 2004).