The study uncovers how ovarian ECM tropism influences endometriotic cell adhesion, paving the way for novel strategies to ...

“The extracellular matrix is critical for maintaining the structure and function of the skin and other tissues, acting as a barrier to the entry of microorganisms and toxins,” Hidalgo explained.

During development, epithelial sheets sculpt organs by folding, either apically or basally, into complex 3D structures. Given the presence of actomyosin networks and cell adhesion sites on both sides ...

Innovations in biotechnology are driving the engineering of tubular organs, providing functional replacements and improving ...

Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk. Med, 2023; 4 (8): 554 DOI: 10.1016/j.medj.2023.07.004 ...

Med, Gnecco and Brown et al. “Organoid co-culture model of the cycling human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk.” https ...

Journal reference: Gnecco, J. S., et al. (2023) Organoid co-culture model of the cycling human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk.

Fibroblasts are found in the connective tissue of our organs, where they ensure that the extracellular matrix is continuously renewed and remains healthy. If an injury occurs or tissue growth is ...

A dynamic load, on the other hand, is a load that repeats itself at a regular time interval, like the forces acting upon your knees while running. Calve runs the Musculoskeletal Extracellular Matrix ...

More information: Hyeonji Kim et al, Extracellular matrix-based sticky sealants for scar-free corneal tissue reconstruction, Biomaterials (2022). DOI: 10.1016/j.biomaterials.2022.121941 ...

Type II epithelial-mesenchymal transition (EMT) plays a vital role in airway injury, repair, and remodeling. Triggered by growth factors, such as transforming growth factor beta (TGFβ), EMT induced a ...

The composition of the extracellular matrix differs between tissue types. Though its main function is to provide an essential scaffold for cells, the extracellular matrix also regulates processes ...