Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the attention of scientists ...

XoZymes replaces traditional chemical production methods with an approach that integrates widely available feedstocks like ...

A recent study published in eLife offers a new perspective on the development of Alzheimer’s disease, suggesting that the ...

For years, scientists have focused on amyloid beta buildup as the main culprit in Alzheimer’s disease, but a new study suggests the real problem might lie in a stalled protein-cutting process in the ...

The manuscript represents a fundamental advance in designing peptide inhibitors targeting Cdc20, a key activator and substrate-recognition subunit ... disordered regions of substrates. As these ...

Department of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China Shanghai Engineering Research Center of ...

Bioluminescence, the natural emission of light by living organisms, is powered by a chemical reaction catalyzed by an enzyme, typically a luciferase, acting on a bioluminescent substrate.

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. The research, published today in eLife, is described by editors as a fundamental study ...

"These findings are in keeping with our 'stalled complex' hypothesis, where it is these enzyme-substrate complexes that trigger neurodegeneration even in the absence of amyloid beta-protein ...

CCM Biosciences has developed groundbreaking compounds that activate the enzyme SIRT3, potentially reversing age-related cellular decline. These first-in-class drugs outperform existing treatments and ...