Research on γ-secretase reveals its unique substrate recognition mechanism, offering potential for developing precise ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental ...

High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, ...

Weizmann Institute of Science-led researchers have unveiled a computational workflow that crafts enzymes exhibiting catalytic ...

This study reports the important development and characterization of next-generation analogs of the molecule AA263, which was previously identified for its ability to promote adaptive ER proteostasis ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

Each year, over 350 million tons of plastic are produced, much of it ending up in landfills or the ocean. A major contributor ...