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AI used to design a multi-step enzyme that can digest some plastics Enzyme mechanisms can be complex, and getting them to work is tricky.
The enzyme, which has been named Huc, is used by the bacterium Mycobacterium smegmatis to draw energy from atmospheric hydrogen, enabling it to survive in extreme, nutrient-poor environments.
Crafting enzymes is more difficult than designing other proteins because it requires not just predicting the structure of a single protein conformation, but of changes in conformations as enzymes ...
Now, researchers have genetically engineered a novel enzyme which can convert ferulic acid from plant waste into vanillin in a one-step sustainable process.
Enzymatic reactions typically occur in aqueous media or with hydrated enzymes. Here, the authors form fluid enzyme-polymer conjugates with sub-solvation levels of water, and demonstrate catalytic ...
Now, Hecht and his colleagues have confirmed that at least one of their new proteins can catalyze biological reactions, meaning that a protein designed entirely from scratch functions in cells as a ...
Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body maintain healthy cholesterol levels—a significant development that could ...
Figuring out how a protein or enzyme works, and understanding how genetic mutations affect these molecules that are fundamental to life, can often take years. Researchers must alter hundreds of ...