New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

A study reveals that the HDAC5 enzyme regulates the gene Scn4b, which affects neuronal activity in the brain's reward regions ...

Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective ...

NASA's SpaceX 32nd commercial resupply services mission, scheduled to lift off from the agency's Kennedy Space Center in ...

Gómez-Sifontes, A. , Diaz-Tablero, J. and Rodriguez, Y. (2025) Anti-C1q Antibodies as Markers of Renal Involvement in Patients with Systemic Lupus Erythematosus, Bolivar City, Venezuela. Open Access ...

Target validation can include: determining the structure-activity-relationship of analogs ... The heme degradation enzyme biliverdin IXβ reductase (BLVRB) is implicated in a redox-regulated ...

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Anti-CCP antibodies were analysed by an enzyme immunoassay (EIA). Rheumatoid factors (RFs) were analysed by latex agglutination and two isotype-specific (IgM and IgA) EIAs. Disease activity was ...

Researchers from the International Institute of Molecular and Cell Biology in Warsaw (IIMCB) have described a new mechanism ...

New research led by the University of Portsmouth has revealed how puppetry and other creative methods can effectively make ...

A research team at the Institute for Basic Science (IBS) has identified a previously unknown enzyme, SIRT2, that plays a key ...