Scientists have known for a while that Alzheimer’s disease affects some areas of the brain more than others. One key player ...

The new research suggests that a subset of inhibitory neurons within the entorhinal cortex, or EC -- an area of the brain essential for forming memories -- continue to migrate into this region ...

The research team led by Nobel Laureates May-Britt and Edvard Moser at the Norwegian University of Science and Technology (NTNU) is already known for their discovery of the brain’s sense of place. Now ...

Our study found that lower thickness of the entorhinal cortex, as measured via brain scan, was associated with higher financial vulnerability, as measured by a self-report questionnaire. We did ...

It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau—a protein known to misbehave—plays an important role in the disease. Normally, tau helps ...

The analysis specifically looks at a brain region called the EC-HPC circuit (including the entorhinal cortex and hippocampus) that plays a key role in memory and is known to be hit early by AD.

Brain areas like the entorhinal cortex and hippocampus succumb early to tau tangles, while other areas, like the primary sensory cortices, remain resilient to the disease. In the quest to better ...

The long-understood model of the studied circuit posits that the hippocampus (HC) receives sensory information about the outside world from entorhinal cortex (EC) surface layers 2 and 3, but sends ...

The sensory cortex is much larger than the hippocampus and can store vast amounts of memory. "Conceptually, we can think about the hippocampus as a pointer network.