The formation of blood vessels is a complex process involving the interplay of proteins and mechanical forces. In two studies ...

Tight junctions are one mode of cell–cell adhesion in epithelial and endothelial cellular sheets. They act as a primary barrier to the diffusion of solutes through the intercellular space ...

Adherens junctions, the structures that allow cohesion between cells in a tissue, appear to be modulated by endothelial cell-to-cell tugging forces.

In endothelial cells, Bcl-xL up-regulates VEGF-A production, 53 and in platelets, Bcl-xL is a major determinant of the life span. 54 Moreover, platelet-derived epidermal growth factor increases ...

Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification. Haematopoietic stem and progenitor cells ...

VASP is crucial for the polymerization of the actin cytoskeleton and is intimately linked to several proteins forming adherens junctions, such as α-catenin. Endothelial cells deficient in VASP ...

When blood moves through your body, it exerts a frictional force on the walls of blood vessels. This force, known as fluid shear stress, has important effects on vascular development, function, and ...

Study shows endothelial cell targeting could help fight COVID-19 symptoms. Dec 14, 2020. What blood platelets and endothelial cells may reveal about COVID-19. Nov 20, 2020.