Many cells comprise the tumor microenvironment, but endothelial cells are particularly crucial. They line blood vessels, regulating blood flow and inflammation, and their cell junctions are the ...

Within this context we are investigating the molecular mechanism that enables leukocytes to overcome the blood vessel wall mainly formed by endothelial cells, a basement membrane ... VE-PTP stabilizes ...

Primary human brain microvascular ECs (HBMVECs; Applied Cell Biology Research Institute, Kirkland, WA, USA) and immortalized primary HBMVECs (hCMEC/D3) were used in experiments with consistent and ...

“Visualizing the impact of Interleukin-32 on Tight Junction Integrity and Nuclear Morphology From Glioblastoma Metastasis in Human Endothelial Cells.” Wheatley School Science Research ...

Following the devastating fires that swept through Los Angeles in January, concerns are on the rise about the long-term health impacts of smoke inhalation.

OBS exhibited higher endothelial cytotoxicity and promoted monocyte-endothelial cell adhesion at concentrations lower than those of PFOS. OBS, not PFOS, disrupted cell junctions and increased ...

A 3D model has been developed that accurately replicates the complex structures of cerebral blood vessels, enabling researchers to mimic the blood–brain barrier.

Discover how a revolutionary 3D Blood-Brain Barrier model advances the understanding of neurodegenerative diseases and drug development.