The formation of blood vessels is a complex process involving the interplay of proteins and mechanical forces. In two studies ...

Instead, we will focus on other functional contacts between platelets and endothelial cells. The most important of these is the maintenance of vascular integrity by the constitutive release of ...

Tight junctions are one mode of cell–cell adhesion in epithelial and endothelial cellular sheets. They act as a primary barrier to the diffusion of solutes through the intercellular space ...

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying severe pneumonia has remained a major research challenge.

Adherens junctions, the structures that allow cohesion between cells in a tissue, appear to be modulated by endothelial cell-to-cell tugging forces. Both the size of junctions and the magnitude of ...

When blood moves through your body, it exerts a frictional force on the walls of blood vessels. This force, known as fluid shear stress, has important effects on vascular development, function, and ...

A team led by the University of Sydney has identified red blood cell rupture at dying endothelial sites as a primary driver of microvascular obstruction in COVID-19, bypassing the expected role of ...

There is a lot of excitement in the field of cell to cell communications. From the well known Gap junctions (small channels between cells) to the lesser known desmosomes (anchor points of contact ...

VASP is crucial for the polymerization of the actin cytoskeleton and is intimately linked to several proteins forming adherens junctions, such as α-catenin. Endothelial cells deficient in VASP ...

Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the University of Colorado Boulder. Findings suggest that erythritol ...

Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification. Haematopoietic stem and progenitor cells ...