Nonspecific major groove DNA-binding domains from both monomers embrace the DNA in a clamp-like structure. The interleaved nucleotide-binding sites are located far from the DNA.

DNA is found in nearly all living cells. However, its exact location within a cell depends on whether that cell possesses a special membrane-bound organelle called a nucleus. Organisms composed of ...

He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s ...

Though scientists have learned much about DNA damage and repair over the past 50 years, important outstanding questions remain. One particularly bedeviling puzzle is how a repair protein called the ...

James Watson and Francis Crick revealed the structure of DNA — the genetic instructions in all living things — 70 years ago in the journal Nature. Watson and Crick could not have succeeded ...

DNA is perhaps the most famous molecule on earth. Here we explain what it is, what it does, and how it is crucial for health.

Despite her contribution to the discovery of DNA's helical structure, Rosalind Franklin was not named a prize winner: She had died of cancer four years earlier, at the age of 37.

Find out how the structure of DNA was discovered by Francis Crick and James Watson, and why the discovery revolutionized science and medicine ...

Explore the 5 key differences between DNA and RNA, including function, structure and location, with examples and insights from modern molecular biology.

Thymine (T) is a key nucleobase in DNA, forming base pairs with adenine and contributing to the genetic code. Learn about its structure, properties, and biological significance.

James Watson and Francis Crick revealed the structure of DNA — the genetic instructions in all living things — 70 years ago in the journal Nature. Watson and Crick could not have succeeded ...