Consistently, our DSS-induced colitis model showed increased colonic FLI-1 expression, which was effectively suppressed by Lumefantrine treatment (Figure 6B). These results establish FLI-1 as a ...

This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell infiltration in obstruction-induced renal fibrosis ...

Results: S1P alleviated DSS-induced colitis by suppressing inflammatory cell infiltration, reducing ulcers, and maintaining intestinal epithelial junction integrity by increasing E-cadherin and ...

DSS-induced acute colitis is largely mediated by macrophages, so any manipulation associated with less severe inflammation is accompanied by lesser macrophage infiltration in this model: this does not ...

Results By comparing the immune and inflammatory responses between wt and CD131-deficient mice, we found that CD131 contributed to DSS-induced murine colitis, which functioned in synergy with tissue- ...

CFP-A reduced the expression levels of interleukin-6 and interleukin-1β and the production of nitric oxide in lipopolysaccharide-induced Raw264.7 macrophages; it also downregulated inflammatory factor ...