A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Nonspecific major groove DNA-binding domains from both monomers embrace the DNA in a clamp-like structure. The interleaved nucleotide-binding sites are located far from the DNA.

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

This study reports the important development and characterization of next-generation analogs of the molecule AA263, which was previously identified for its ability to promote adaptive ER proteostasis ...

A photoswitchable, DNA structure-specific small-molecule probe, named G4switch, has been developed for the reversible targeting of DNA G-quadruplexes (G4s) in vitro and within cells.

There is no change in price structure, label, source and warehouse among others in case of existing licences/registered brands active upto June 30, said the notice.

Mayo Clinic's Nucleic Acid Structure and Recognition Lab studies how the DNA double helix can be folded and looped during packaging and gene expression.

The Delhi government has extended its excise policy for the financial year 2025-26 even as work is underway to come up with a new regime to regulate liquor trade in the national capital.