Van Andel Research Institute. "New study reveals the structure of DNA helicase at the replication fork." ScienceDaily. www.sciencedaily.com / releases / 2017 / 01 / 170116160548.htm (accessed May ...

The replication fork is more than just a means for DNA duplication. It is connected to a checkpoint system that keeps the genome intact and prevents cancer. Aa Aa Aa Eukaryotic genomes are ...

Given its importance, DNA replication is tightly regulated, primarily upon initiation at genomic sites known as origins of replication. A two-pronged structure known as a replication fork forms at ...

The replication terminator protein (RTP) of Bacillus subtilis is one of only two well-characterized proteins known to cause DNA replication fork arrest 1,2,3.It is a 29 kDa dimeric member of the ...

Stylized DNA replication fork with nucleotides matched, 5'->3' synthesis shown, no enzymes in diagram. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted ...

In the new study, Spies’ team used cryogenic electron microscopy (CryoEM) to show that RAD52 proteins form an unexpected spool-like structure composed of two rings of RAD52, each containing 11 copies ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

However, the process of DNA replication intrinsically disrupts nucleosomes ahead of the fork raising the question how chromatin structure is maintained across generations. Nucleosomes are re-assembled ...

Mitochondrial DNA is compact in structure and typically lacks non-coding regions ... The replication fork continues for a total of two-thirds of the genome before encountering the O L.