Across two new papers published Wednesday (July 23) in the journal Nature, scientists sequenced the DNA of 1,084 people ...

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

San Diego BioMed congratulates the Gilbert Lab for their recent publication! Read @ The EMBO Journal: Professor Gilbert has provided an engaging commentary on this manuscript and his lab’s work below ...

Here, we reconstitute replication of physiologically derived structure‐forming sequences to find that a single G4 or iM arrest DNA replication. Direct single‐molecule structure detection within ...

Background The elimination of HBV covalently closed circular DNA (cccDNA) remains a critical hurdle for ... Combination therapy with IFN-α effectively suppressed HBV replication, achieving a 60% ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

Recent findings reveal that early mouse embryos replicate their DNA in a unique, uniform manner, which changes after the embryo grows beyond four cells. This early-stage replication is slower and more ...

2 Structure of replication origin regions DNA replication initiation in bacteria starts with replication initiation proteins binding with the specific motifs within a well-defined origin region ...