This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Other combinations of the atoms form the four bases: thymine (T), adenine (A), cytosine (C), and guanine (G). These bases are the rungs of the DNA ladder. (It takes two bases to form a rung -- one ...

With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans. Now, researchers at Harvard University have designed a new class ...

Ribonucleic acid (RNA) is a linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

GenAssist’s IND application for GEN6050X receives US FDA clearance, a globally first-in-class base editing drug for duchenne muscular dystrophy: Suzhou, China Friday, March 7, 2 ...

Six of these polymorphisms are single base pair substitutions, although one involves the simple repeat of cytosine residues at nt 311–315. The CRS has five residues in this repeat, whereas most ...

The thymine-adenine (T-A) base pair is held together by fewer hydrogen bonds compared to the guanine-cytosine (G-C) base pair, which has three hydrogen bonds. The complementary base pairing in DNA ...