Based on human and mouse cell cultures, they were able to show that ergothioneine acts as an alternative substrate for the enzyme cystathionine-γ-lyase (CSE). This enzyme plays a central role in ...
In detail, this study revealed how an amino acid change (T236N) in an enzyme called cystathionine-synthase (CBS) causes it to malfunction. CBS is an enzyme that helps break down homocysteine ...