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Using the Atacama Large Millimeter/submillimeter Array (ALMA), a team of astronomers led by Abubakar Fadul from the Max ...
Hippocampal single-cell RNA Atlas of chronic methamphetamine abuse-induced cognitive decline in mice
The authors proposed two hypotheses: first, that methamphetamine induces neuroinflammation, and second, that it alters neuronal stem cell differentiation. These are valuable hypotheses, and the ...
Sumitomo Chemical has launched a new digital transformation (DX) management structure. The Company will reform its organization and systems for DX strategy planning and execution and accelerate ...
This method involves information referred to as a label, such as the physical property of a chemical structure, that “supervises” the way a model learns to predict properties from structures.
Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using cryo-electron microscopy.
In a study published in Cell Research, a research team has, for the first time, resolved the high-resolution in situ structure of the central apparatus (CA) within the axoneme of mammalian sperm.
The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...
Boltz-2 is an open-source biomolecular model achieving near-FEP accuracy with 1000x faster predictions for structure and binding affinity. Quiver AI Summary MIT and Recursion have released Boltz-2 ...
The MIT model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.
Researchers have discovered three compounds with anti-aging properties produced by a bacterium in the blood, which reduced damage and inflammatory responses.
Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, ...
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