Cohesin plays a crucial role in both chromosome organization and DNA repair. Here the authors find that cohesin mediated genome architecture prevents interactions between damaged chromatin.

DNA (deoxyribonucleic acid) is the nucleic acid polymer that forms the genetic code for a cell or virus. Most DNA molecules consist of two polymers (double-stranded) of four nucleotides that each ...

It then selects the necessary columns (chromosome, position, strand, and label) and binarizes the labels. The core of this project is a convolutional neural network (CNN) designed to predict the ...