There are several reasons why you might have high complement C4 levels over 45 milligrams per deciliter. If you have had a recent injury or infection, you’re likely to have more C4 in your blood.

The complement system, which was discovered more than 100 years ago, is one of the oldest components of immunity and is central to the detection and destruction of invading pathogens 1,2,3,4,5.

The complement system plays a part in glomerular disease. There are two main forms of glomerular disease: dense deposit disease and C3 glomerulonephritis. Learn more about them both.

The complement system is a part of the innate immune system, which serves as the first line of defense against germs. The complement system activation helps elicit an immune response against ...

Disruption of the complement system appears to precede the onset of islet autoimmunity (IA), making it a potential early warning sign of type 1 diabetes (T1D), according to a new report.

The immune system has evolved to act as a first responder against infections, and scientists have revealed how it knows when to activate.

But if the complement system remains in its microbe-fighting state after the viruses and bacteria are eliminated, “it starts damaging healthy cells,” he said.

Researchers have discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly ...

The complement system plays a major role in the pathogenesis of ischemia-reperfusion injuries such as HIE. We have previously demonstrated that HT modulates complement activity in vitro.