As Brenner explains, leaking blood vessels allow complement proteins to target brain tissue, causing the immune system to mistakenly launch an attack on the body's own cells and worsen patient ...

Taken together, these data support the complement cascade, mTOR, interferons, neutrophils, and NETs as major points of interest in antiphospholipid syndrome pathogenesis and potential treatment ...

This trial also unveils the value of complement inhibitors in managing other rare glomerular diseases that may be complement-mediated. What is your research’s relevance to human disease? This pivotal ...

Should I Treat This Patient With Geographic Atrophy? Weighing Benefits and Burden of Treatment With Complement Inhibitors Supported by an educational grant from Astellas.

Annexon, Inc. announced significant progress in its clinical development programs, particularly focusing on its lead investigational therapies aimed at treating classical complement-mediated ...

Challah French toast is a simple but indulgent breakfast to make Mom on Mother’s Day An eggy bread like challah is a great choice for French toast.

‘Another Simple Favor’ review: Sequel sticks to what (mostly) works Lively and, especially, Kendrick are enjoyable again in mildly enjoyable second affair ...

A 6-hour morning routine? First, try a few simple habits to start your day A viral video has gotten people talking about how best to start your day.

A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement system in human tissue, a discovery that could reshape the treatment of many rheumatic ...

Specifically, the complement activation, which triggers neutrophils’ phagocytosis, is enhanced in response to the negatively charged liposomes. Our findings highlight an opportunity to improve ...

By silencing C3, investigational ARO-C3 has the potential to treat complement-mediated renal diseases by modulating the activation of the complement cascade.